The Role of Salvage Prostatectomy for Radiation Failure in Prostate Cancer.

Pts must have biopsy proven persistence or recurrence of prostate cancer with no evidence of metastatic disease at the time of biopsy. Pts must have a PS of 0-1. Pts must have been treated with >/= 60 cGy external beam RT or brachytherapy for clinical states T1-2, NX, M0 PC w/PSA < / = to 30 ng/ml prior to RT. It must be > / = 18 mos since last RT and > / = to 3 mos since last adj hormonal tx. Pts dx'ed w/another malignancy w/in previous 5 years (except for non-melanoma skin ca or Ta bladder ca) are not eligible. Pts must have a PSA of < / = 20 ng/ml obtained within 30 days prior to registration.