SWOG clinical trial number
CTSU/C90601

A Randomized Double-Blinded, Phase III Study Comparing Gemcitabine, Cisplatin, and Bevacizumab to Gemcitabine, Cisplatin, and Placebo in Patients with Advanced Transitional Cell Carcinoma.

Closed
Phase
Abbreviated Title
Advanced TCC, Gemcitabine, Cisplatin +/- Bevacizumab, Ph III
Activated
08/15/2009
Closed
12/02/2014
Participants
CTSU

Research committees

Genitourinary Cancer

Treatment

Cisplatin Gemcitabine hydrochloride Bevacizumab

Eligibility Criteria Expand/Collapse

The Southwest Oncology Group has endorsed this study through the Cancer Trials Support Unit (CTSU) of the National Cancer Institute.

Please contact the CTSU directly by either phone (1-888-823-5923) or on the CTSU web site (http://www.ctsu.org/) for information and registration procedures.

Publication Information Expand/Collapse

2025

Relationship among DNA damage response gene alterations, molecular subtypes, and survival outcomes in patients with metastatic bladder cancer treated on CALGB 90601

G Iyer;W Choi;B Luo;F Carvalho;T Hanlon;H Reis;B Guerico;M Fong;J Mountain;M Feng;A Regazzi;A McCart;Y Wen;H Al-Ahmadie;K Mouw;E Van Allen;J Bellmunt;R Dreicer;T Flaig;S Halabi;D McConkey;J Rosenberg JCO Precision Oncology

PMid: PMID40591902

2021

Randomized Phase III Trial of Gemcitabine and Cisplatin With Bevacizumab or Placebo in Patients With Advanced Urothelial Carcinoma: Results of CALGB 90601 (Alliance)

J Rosenberg;K Ballman;S Halabi;P Atherton;R Dreicer;C Holmes;W Stadler;E Plimack;T Flaig;R Dreicer;B Teply;J Pincus;S Tagawa;D Vaena;J Misleh;A Shipstone;A Mortazavi;M Morris Journal of Clinical Oncology Aug 1;39(22):2486-2496; May 14;JCO2100286. doi: 10.1200/JCO.21.00286. Online ahead of print

PMid: PMID33989025

2019

CALGB 90601 (Alliance): Randomized, double blind, placebo-controlled phase III trial comparing gemcitabine and cisplatin with bevacizumab or placebo in patients with metastatic urothelial carcinoma

J Rosenberg;K Ballman;S Halabi;C Watt;R Dreicer;T Flaig;M Morris J Clin Oncol 37(suppl; abstr 4503); American Society of Clinical Oncology (5/31-6/4/19, Chicago IL), oral

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