Prostate Cancer Intervention Versus Observation Trial

Age < /= 75 yrs; Clinically localized tissue documented adenoca. of the prostate, (T1 a,b,c, - T2 a,b,c, NX, M0); Diagnosis of CAP within previous 6 mo; PSA < 50 ng/ml,(if currently taking finasteride, PSA < 25 ng/ml); no prior pelvic RT, chemo, anti-androgen or androgen deprivation therapy except 5-alpha-reductase inhibitors; no prior surg. other than TURP/TUIP/dilation/simple prostatectomy; no current estrogen or androgen blocking therapy; no evidence of metastatic dz., no significant medical conditions or high surgical risks (MI within last 6 mo, unstable angina, severe CHF pulmonary or hepatic dz, see p. 31 of the Manual of Operations for complete description).