SWOG clinical trial number
SWOG-8591(NCI Intergroup #0035)

An Evaluation of Levamisole Alone or Levamisole plus 5-Fluorouracil as Surgical Adjuvant Treatment for Resectable Adenocarcinoma of the Colon

Closed
Phase
Published
Abbreviated Title
An Evaluation of Levamisole Alone or Levamisole plus 5-Fluorouracil as Surgical Adjuvant Treatment for Resectable Adenocarcinoma of the Colon
Activated
01/14/1985
Closed
10/01/1987

Research committees

Gastrointestinal Cancer

Publication Information Expand/Collapse

2017

The effect of positive SWOG treatment trials on survival of patients with cancer in the US population

JM Unger;M Leblanc;CD Blanke JAMA Oncology Oct 1;3(10):1345-1351

PMid: PMID28586789; PMC5710507

The impact of positive SWOG treatment trials on population survival

J Unger;M LeBlanc;C Blanke J Clin Oncol 35, 2017 (suppl; abstr 6513); American Society of Clinical Oncology Annual Meeting (June 2-6, 2017, Chicago, IL), poster discussion

2009

Racial disparities in survival of patients with sex-specific cancers treated on Southwest Oncology Group clinical trials. PMC2724852; PMID: 19584328

KS Albain;JM Unger;JJ Crowley;CA Coltman;DL Hershman Journal of the National Cancer Institute 101(14):984-992

2008

The Southwest Oncology Group: progress in cancer research [PMID18929152]

CA Coltman Seminars in Oncology 35(5):545-552

2005

Differences in toxicity between men and women treated with 5-fluorouracil therapy for colorectal carcinoma

K Chansky;J Benedetti;JS Macdonald Cancer 103(6):1165-1171

2001

A pooled analysis of adjuvant chemotherapy for resected colon cancer in elderly patients

DJ Sargent;RM Goldberg;SD Jacobson;JS Macdonald;R Labianca;DG Haller;LE Shepherd;JF Seitz;G Francini New England Journal of Medicine 345(15):1091-1097

2000

Clinical correlation for colorectal cancers with microsatellite instability (MSI)

DP Chauhan;LC Lovato;A Goel;T Aoki;CR Boland;DJ Ahnen Gastroenterology 118(4)Suppl:A58(#499)

1998

Surgery for recurrent colon cancer: Strategies for identifying resectable recurrence and success rates after resection.

RM Goldberg;TR Fleming;CM Tangen;CG Moertel;JS Macdonald;DG Haller;JA Laurie Annals of Internal Medicine 129(1):27-35

1995

Fluorouracil plus levamisole as effective adjuvant therapy after resection of stage III colon carcinoma: A final report.

CG Moertel;TR Fleming;JS Macdonald;DG Haller;JA Laurie;CM Tangen;JS Ungerleider;WA Emerson;DC Tormey;JH Glick;MH Veeder;JA Mailliard Annals of Internal Medicine 122(5):321-326

The Intergroup Study of fluorouracil plus levamisole as adjuvant therapy for stage II/Dukes' B2 colon cancer.

CG Moertel;TR Fleming;JS Macdonald;DG Haller;JA Laurie;CM Tangen;JS Ungerleider;WA Emerson;DC Tormey;JH Glick;MH Veeder;JA Mailliard Journal of Clinical Oncology 13(12):2936-2943

1993

Recognition and salvage of the patient with recurrent colon cancer.

C Moertel;T Fleming;J Macdonald;D Haller;J Laurie;C Tangen ASCO 12:224(#688)

Testing against ordered alternatives for censored survival data.

PY Liu;S Green;M Wolf;J Crowley JASA 88(421):153-160

An evaluation of the carcinoembryonic antigen (CEA) test for monitoring patients with resected colon cancer

CG Moertel;TR Fleming;JS Macdonald;DG Haller;JA Laurie;C Tangen JAMA 270(8):943-947

Hepatic toxicity associated with fluorouracil plus levamisole adjuvant therapy

CG Moertel;TR Fleming;JS Macdonald;DG Haller;JA Laurie Journal of Clinical Oncology 11(12):2386-2390

1992

The Intergroup study of fluorouracil (5-FU) plus levamisole (LEV) and levamisole alone as adjuvant therapy for stage C colon cancer. A final report.

C Moertel;T Fleming;J Macdonald;D Haller;J Laurie ASCO 11:161(#457)

1990

Levamisole and fluorouracil for adjuvant therapy of resected colon carcinoma.

CG Moertel;TR Fleming;JS Macdonald;DG Haller;JA Laurie;PJ Goodman;JS Ungerleider;WA Emerson;DC Tormey;JH Glick;MH Veeder;JA Mailliard NEJM 322:352-358

Other Clinical Trials

SWOG Clinical Trial Number
SWOG-8037

Combined Therapies for Squamous Cell Carcinoma of the Esophagus

Research Committee(s)
Gastrointestinal Cancer
Activated
02/16/1981
Closed
01/19/1984
Closed
Phase
II
Published
SWOG Clinical Trial Number
SWOG-8591(NCI Intergroup #0035)

An Evaluation of Levamisole Alone or Levamisole plus 5-Fluorouracil as Surgical Adjuvant Treatment for Resectable Adenocarcinoma of the Colon

Research Committee(s)
Gastrointestinal Cancer
Activated
01/14/1985
Closed
10/01/1987
Closed
Phase
Published
SWOG Clinical Trial Number
SWOG-8721

A Phase II Trial of Trimetrexate in the Treatment of Esophageal Cancer

Research Committee(s)
Gastrointestinal Cancer
Activated
09/01/1987
Closed
09/01/1991
Accrual
69%
Closed
Phase
II
Published