SWOG clinical trial number
S2506

MOZART MZL: A Randomized Phase II Study with a Common Control Arm of Mosunetuzumab Monotherapy Evaluated Against Two Experimental Treatment Arms of Either Combination Mosunetuzumab and Zanubrutinib or Mosunetuzumab and Polatuzumab Vedotin for the Treatment of Patients with Relapsed/Refractory Marginal Zone Lymphoma

Open
Phase
Accrual
0%
Abbreviated Title
Testing mosunetuzumab alone, with zanubrutinib, and with polatuzumab vedotin for treating marginal zone lymphoma that came back or didn’t get better with treatment
Status Notes
Effective 08/18/2026, S2506 is open to accrual.
Activated
08/18/2026
Participants
ALL NATIONAL CLINICAL TRIALS NETWORK MEMBERS

Research committees

Lymphoma

Treatment

Mosunetuzumab Polatuzumab vedotin Zanubrutinib