A Study Evaluating the Pregnancy Outcomes and Safety of Interrupting Endocrine Therapy for Young Women with Endocrine Responsive Breast Cancer who Desire Pregnancy

Closed

Phase

Abbreviated Title

Study Evaluating the Pregnancy Outcomes and Safety of Interrupting Endocrine Therapy for Women with Endocrine Responsive BC

Activated

10/15/2015

Closed

12/31/2019

Participants

ALL NATIONAL CLINICAL TRIALS NETWORK MEMBERS LISTED ON TITLE PAGE

Research committees

Breast Cancer

Cancer Survivorship

Eligibility Criteria Expand/Collapse

Eligibility criteria are accessible from the protocol abstract page on the CTSU website (http://www.ctsu.org).

Publication Information Expand/Collapse

2025

Breastfeeding after hormone-receptor positive breast cancer: results from the POSITIVE trial

F Peccatori Journal of Clinical Oncology, 2025 Aug 20;43(24):2712-2719. doi: 10.1200/JCO-24-02697. Epub 2025 Jul 9.

PMid: 40632989

Hormonal factors predictive of fertility in patients with breast cancer interrupting adjuvant endocrine therapy to attempt pregnancy in POSITIVE trial (IBCSG 48-14/BIG 08-13/Alliance A221405)

Demeestere I Breast. 2025 Oct;83:104547. doi: 10.1016/j.breast.2025.104547. Epub 2025 Jul 26.

PMid: PMID40743662 | PMC number: PMC12336806

2024

Fertility preservation and assisted reproductive technologies in breast cancer patients interrupting adjuvant endocrine therapy to attempt pregnancy

H Azim;S Niman;A Partridge;I Demeestere;M Ruggeri;M Colleoni;M Colleoni;C Saura;C Shimizu;A Satersdal;J Kroep;A Mailliez;E Warner;V Borges;F Amant;A Gombos;A Kataoka;C Rousset-Jablonski;S Borstnar;J Takei;J Lee;J Walshe;M Ruiz Borrego;H Moore;C Saunders;V Bjelic Radisic;S Susnjar;F Cardoso;N Klar;T Spanic;K Ruddy;M Piccart;L Korde;A Goldhirsch;R Gelber;O Pagani;F Peccatori Journal of Clinical Oncology 2024 Aug 10;42(23):2822-2832. doi: 10.1200/JCO.23.02292. Epub 2024 May 29.

PMid: PMID38810178

2023

Interrupting Endocrine Therapy to Attempt Pregnancy After Breast Cancer

AH Partridge;S Niman;M Ruggeri;F Peccatori;H Azim;M Colleoni;C Saura;C Shimizu;A Saetersdal;J Kroep;A Mailliez;E Warner;V Borges;F Amant;A Gombos;A Kataoka;C Rousset;S Borstnar;J Takei;J Lee;J Walshe;M Ruiz Borrego;HCF Moore;C Saunders;V Bjelic-Radisic;S Susnjar;F Cardoso;K Smith;T Ferreiro;K Ribi;K Ruddy;R Kammler;S El-Abed;G Viale;M Piccart;L Korde;A Goldhirsch;R Gelber;O Pagani New England Journal of Medicine May 4;388(18):1645-1656

PMid: PMID37133584 | PMC number: PMC10358451