SWOG clinical trial number
SWOG-9438
Total Body Irradiation, Etoposide, Cyclophosphamide and Autologous Peripheral Blood Stem Cell Transplantation Followed by Randomization to Therapy With Interleukin-2 Versus Observation for Patients With Non-Hodgkin's Lymphoma, A BMT Study, Phase III
Closed
Phase
Accrual
98%
Published
Abbreviated Title
NON-HODGKIN'S: Debulking salvage chemo adn stem cell harvest -> TBI/cyclophosphamide -> PBSCT and randmization to IL-2 or obs.
Activated
05/15/1995
Closed
07/01/2004
Participants
Limited Institutions: BMT Members
Research committees
Lymphoma
Treatment
Cyclophosphamide
Allopurinol
Interleukin-2
Trimethoprim sulfa
VP-16
Radiation Therapy
Eligibility Criteria Expand/Collapse
Biopsy proven low, intermediate or high grade NHL (D-H & J); relapsed following CR or PR or no response to prior therapy (as listed in protocol); age 16-60; HIV neg; no prior BMT; no CNS involvement; no hist. of seizures; no heart problems; no allergy to VP-16; no prior IL-2; no prior involved field RT; no autoimmune
disease or prior allogeneic organ transplant.
disease or prior allogeneic organ transplant.
Publication Information Expand/Collapse
2013
PMid: PMID23669424 | PMC number: PMC4131693
2008
Total body irradiation, etoposide, cyclophosphamide and autologous peripheral blood stem cell transplantation followed by randomization to therapy with Interleukin-2 versus observation for patients with non-Hodgkin's lymphoma: Results of a Phase III randomized trial by the Southwest Oncology Group (SWOG 9438) [PMC2288718; PMID18256325]
2004
Impact of increased body weight on acute toxicity and outcome of autologous stem cell transplantation for non-Hodgkin's lymphoma: a Southwest Oncology Group analysis
Other Clinical Trials
SWOG Clinical Trial Number
S2207
Randomized Phase II Study of the Addition of Targeted Therapeutic Agents to Tafasitamab-Based Therapy in Non-Transplant-Eligible Patients with Relapse/Refractory Large B-Cell Lymphoma
Research Committee(s)
Lymphoma
Activated
06/30/2023
Accrual
6%
Open
Phase
SWOG Clinical Trial Number
CTSU/AHOD2131
A Randomized Phase 3 Interim Response Adapted Trial Comparing Standard Therapy with Immuno-oncology Therapy for Children and Adults with Newly Diagnosed Stage I and II Classic Hodgkin Lymphoma
Research Committee(s)
Lymphoma
Immunomolecular Therapeutics
Activated
04/28/2023
Open
Phase
SWOG Clinical Trial Number
S2114
A Randomized Phase II trial of consolidation therapy following CD19 CAR T-cell treatment for Relapsed/Refractory Diffuse Large B-cell Lymphoma or Grade IIIB Follicular Lymphoma
Research Committee(s)
Lymphoma
Activated
02/23/2023
Accrual
12%
Open
Phase