Limited Institution Pilot Trial of Alpha Interferon with Combination Chemotherapy in Disseminated Malignant Melanoma, Phase II

Closed

Phase

Accrual

39%

Published

Abbreviated Title

Phase II Disseminated Malignant Melanoma

Activated

08/01/1994

Closed

11/13/1996

Research committees

Melanoma

Publication Information Expand/Collapse

2008

Meta-analysis of phase II cooperative group trials in metastatic stage IV melanoma to determine progression-free and overall survival benchmarks for future phase II trials. [PMID18235113]

EL Korn;PY Liu;SJ Lee;JAW Chapman;D Niedzwiecki;VJ Suman;J Moon;VK Sondak;MB Atkins;EA Eisenhauer;W Parulekar;SN Markovic;S Saxman;JM Kirkwood Journal of Clinical Oncology 26(4):527-534

1999

Phase II trial of biochemotherapy with interferon a, dacarbazine, cisplatin and tamoxifen in metastatic melanoma: A Southwest Oncology Group trial.

KA Margolin;PY Liu;JM Unger;WS Fletcher;LE Flaherty;WJ Urba;EM Hersh;LF Hutchins;JA Sosman;JW Smith;GR Weiss;VK Sondak Journal of Cancer Research and Clinical Oncology 125:292-296

Other Clinical Trials

SWOG Clinical Trial Number

CTSU/EA6174

A Phase III Randomized Trial Comparing Adjuvant MK-3475 (Pembrolizumab) to Standard of Care Observation in Completely Resected Merkel Cell Carcinoma

Research Committee(s)

Melanoma

Activated

10/01/2018

Open

Phase

SWOG Clinical Trial Number

CTSU/EA6141

Randomized Phase II/III Study of Nivolumab plus Ipilimumab plus Sargramostim versus Nivolumab plus Ipilimumab in Patients with Unresectable Stage III or Stage IV Melanoma

Research Committee(s)

Melanoma

Activated

09/10/2015

Open

Phase

SWOG Clinical Trial Number

CTSU/EA6134

A Randomized Phase III Trial of Dabrafenib + Trametinib Followed by Ipilimumab + Nivolumab at Progression vs. Ipilimumab + Nivolumab Followed by Dabrafenib + Trametinib at Progression in Patients with Advanced BRAFV600 Mutant Melanoma

Research Committee(s)

Melanoma

Activated

07/13/2015

Open

Phase