SWOG clinical trial number
S1316

Prospective Comparative Effectiveness Trial for Malignant Bowel Obstruction

Open
Phase
III
Accrual
100%
Abbreviated Title
Surgery vs Non-Surgical Management for MBO
Status Notes
Re-Activation - Effective 6/1/18
Activated
03/09/2015
Participants
ALL NATIONAL CLINICAL TRIALS NETWORK MEMBERS LISTED ON TITLE PAGE

Research committees

Cancer Survivorship
Gastrointestinal Cancer

Treatment

Surgery Non-surgical management

Other Study Materials

Eligibility Criteria Expand/Collapse

Must have malignant bowel obstruction (MBO); must have MBO due to an intra-abdominal primary cancer; must be able to tolerate a major surgical procedure based on clinical evaluation, status of their cancer, and any other underlying medical problems; a member of the surgical team must indicate equipoise for the benefit of the surgical treatment for MBO; pts must not have signs of bowel perforation or "acute" abdomen as evidenced by free air on radiologic imaging or peritonitis on a physical exam within 2 days prior to reg; must be registered within 3 days after surgical consult for MBO and prior to any treatment for MBO; Zubrod PS 0-2 within 7 days prior to reg; must plan to collect serum albumin after admission, but prior to treatment; must be able to complete study questionnaires in English; must be >/= 18 years old.

Publication Information Expand/Collapse

2020

Sociocultural Factors of Cancer Clinical Trial Recruitment and Multidisciplinary Team Recruitment of Latin-American Patients in Mexico, Peru and Colombia

D Isla;R Krouse;A Mohar;A Leon;M Sanchez;O Guevara;M Lopez;LG Mora;N Macavilca;IC Carrillo International Conference on Advancing the Science of Cancer in Latinos (Feb 26-28, 2020, San Antonio, TX), poster

2019

Intellectual Equipoise and Challenges: Accruing Patients with Advanced Cancer to a Trial Randomizing to Surgical or Non-Surgical Management (SWOG S1316)

G Deutsch;J Deneve;M Al-Kasspooles;V Nfonsam;C Gunderson;A Alvarez Secord;P Rodgers;S Hendren;E Silberfein;ML Grant;J Sloan;V Sun;K Arnold;G Anderson;R Krouse American Journal of Hospice & Palliative Medicine Jan;37(1):12-18; May 23 [Epub ahead of print]

PMid: PMID31122027 | PMC number: PMC6868288

2015

Prospective comparative effectiveness trial for malignant bowel obstruction: SWOG S1316

RS Krouse American College of Surgeons Bulletin Dec;100(12):49-50

PMid: PMID26749971

Reports & Approvals

Trial Locations

Other Clinical Trials

SWOG Clinical Trial Number
S1922

Randomized Phase II Study of Ramucirumab and Paclitaxel versus FOLFIRI in Refractory Small Bowel Adenocarcinoma

Research Committee(s)
Gastrointestinal Cancer
Activated
12/16/2019
Accrual
0%
Open
Phase
II
SWOG Clinical Trial Number
S1815
SWOG Clinical Trial Number
S1613